Did anyone at the last supper become intoxicated to any degree?
The Bible does not say. If I were Judas, it might have been a good idea! No, seriously, I think we American's have a hard time with alcohol because so many of
us abuse it. A missionary who came to my church once reported that in other cultures, beer (i.e. alcohol) is perfectly acceptable for Christians, but coffee and the like, which have caffeine, are totally unacceptable because caffeine is highly addictive. The Bible does not mention caffeine at all. I think the point the Bible makes is
when you drink alcohol, do it for medicinal purposes (there is a mention of that, can't remember where, but it is in the New Testament), or as a part of a celebration, (Jesus celebrated at the wedding), but don't make a fool of yourself by overindulging and acting like an idiot or by drinking so as to become an addict; an addiction becomes an idol in this case, since you are putting your drug of choice before God and depending on the drug to "solve" or at least "numb" your problems.
That all being said, No, I do not think it is a
sin to drink alcohol responsibly, that is, like you would drink any other beverage. Do you drink water or orange juice or any other beverage until it makes you pass out? You can drink enough water in a short period of time that it will kill you, you know. Use your common sense and you will be ok.