We demonstrated that SARS-CoV-2 spike glycoprotein (S) directly binds to the CD4 molecule, which in turn mediates the entry of SARS-CoV-2 in T helper cells. This leads to impaired CD4 T cell function and may cause cell death. SARS-CoV-2-infected T helper cells express higher levels of IL-10, which is associated with viral persistence and disease severity. Thus, CD4-mediated SARS-CoV-2 infection of T helper cells may contribute to a poor immune response in COVID-19 patients.
In other words, the spike protein’s CD4-attacking feature seems almost designed to avoid the human immune response. Just what you’d want in a bioweapon, for example.Infection of CD4+ T cells by SARS-CoV-2 could explain lymphocytopenia and dysregulated inflammatory response in severe COVID-19 patients. Moreover, from an evolutionary perspective, infection of CD4+ T cells represents an effective mechanism for viruses to escape the immune response.
I was cleaning out the drawer under my passenger's seat in my car and ran across a bundle of old masks that I never wore. Went maskless as much as I could and avoided (thanks to a sympathetic manager) the "mandatory" jab in Year two.Still unjabbed, I kept livin my life
Well, that didn't age very well. Anyone who hasn't seen The Plandemic parts one and two needs to. It's literally a matter of life and death.I've pretty much given up on this site. I only hang around here to counter the COVID conspiracy nonsense. You will never convince some people of reality. Their alternate reality is part of their identity.
I live in Israel, where the vaccine has been a great success. I urge everybody to get vaccinated, as soon as possible.
...and then there's Alex. I have never understood why interviewers continually interrupt their guests mid point and try to steer the conversation where they want it to go if they are genuinely interested in what they have to say in the first place.Sean Hannity is even worse about interrupting like that.