Indeed! The fact that the scientific method - that is the ACTUAL scientific method - works at all, turns out to be proof that the materialist worldview is self defeating by its own terms and therefore MUST be false...
If materialism is true, then all our thoughts are the result of nonrational physical causes.
If all our thoughts are the result of nonrational physical causes, then we have no reason to trust them as rationally true.
Therefore, if materialism is true, we have no reason to believe it is true.
In short: Materialism undercuts the rational basis required to affirm materialism.
QED
For the materialist, declaring anything to be true or false, the very act of affirming any knowledge at all, is the act that undermines his own worldview.